The With Office issued a rare red alarm warning of danger to life as storm Arwen is said to have brought strong winds and snow.
Meteorologists have warned of chaos on travel, as the first winter storm is expected to hit parts of north-east England and Scotland with gusts of up to 80-90 mph.
The red wind warning applies to those areas between 3pm on Friday and 2am on Saturday when roofs could be blown away and flying debris could be life-threatening.
The Met Office also expects power outages and the closure of roads, bridges and railways.
Snow warnings were also issued for much of northern England and Scotland by 10am on Saturday.
Scottish Transport Minister Graeme Day urged people traveling to take the weather into account, saying: “The whole country will be windy, but the Met Office informs us that especially the eastern parts of Scotland will experience some difficult weather. ”
The Met Office names the storms based on their potential impact, and storm Arwen was declared as a result of a red wind warning.
Stephen Dixon, a Met Office spokesman, said the areas hardest hit by strong winds will be mostly on the coast.
He added: “As Arwen is causing disturbances, there is likely to be snow in the coming days, especially in the higher parts of Scotland and the north of England.
“There may also be some snow in the lower part of northern England, although this is likely to be short-lived and will fall in the form of hail or winter rain.
“This is due to a drop in temperature, with parts of rural Scotland and England dropping below freezing at night.”
The RAC advised drivers to prepare for strong shocks by slowing down speed and being “very careful” when passing by tall side vehicles or cyclists.
Spokesman Simon Williams said: “In extreme wind conditions, bridges can also be closed and trees can fall, so it’s important to allow yourself extra time to travel.
“As forecasters predict strong winds along with colder conditions, drivers should take this opportunity to prepare their vehicles for winter by checking oil and coolant levels and ensuring they have enough quality washer glass to protect up to well below minus 10C and inflated tires with a good profile. ”
Additional Reporting Press Association