The study says COVID-19 can block cannabis compounds

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Compounds found in cannabis can prevent the virus that causes it COVID-19 since entering human cells, a new study published in Journal of Natural Products.

Researchers at Oregon State University found that a pair of cannabinoid acids binds to the spike protein in SARS-CoV-2, the virus that causes COVID-19. This blocks spike protein from binding to angiotensin converting enzyme-2 (ACE-2) receptors. The spike protein gets stuck to ACE 2 receptors located in the lining of the lungs and other organs, causing the virus to infect humans, health experts explained. Fox News.

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“This means that inhibitors of uptake into cells, such as hemp acids, could be used to prevent SARS-CoV-2 infection and also to shorten infections by preventing viral particles from infecting human cells,” said Richard Van Breemen. , a researcher at Oregon State’s Global. Cannabis Innovation Center, Faculty of Pharmacy and Linus Pauling Institute v Published by Oregon State University.

In this photo, on Tuesday, July 2, 2019, Darren Johnson, a cannabis processor, is holding raw cannabis that will be used to make CBD oil at his Wasatch Extraction plant in Salt Lake City. Johnson is one of 81 applicants vying for a license to grow medical marijuana in Utah.
(AP Photo / Morgan Smith)

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Two cannabis products, called cannabigellic acid or CBGA, and cannabidiol acid, CBDA, had the highest affinity for tip proteins and were confirmed to block virus infection, Van Breemen said in an OSU issue.

Cannabis is known as Cannabis sativa and many cannabis extracts and compounds are added to body lotions, cosmetics, dietary supplements., and food, according to the publication. Cannabis also serves as a source of food, fiber and animal feed, the researchers said in a report.

In a press release, the researchers explained that these cannabinoid acids are abundant in cannabis and many cannabis extracts. “They are not controlled substances like THC, the psychoactive ingredient in marijuana, and have a good safety profile in humans,” Van Breemen said in an OSU edition.

“They have the potential to prevent and also treat SARS-CoV-2 infection. CBDA and CBGA are produced by the cannabis plant as a precursor to CBD and CBG, known to many consumers. However, they differ from acids and are not found in cannabis products.” Van Breemen said in a statement.

Jim Castetter, head of sales at Empire Standard, a cannabis extract processing and distribution plant, weighs hemp flowers on a scale on April 13, 2021 in Binghamton, New York.

Jim Castetter, head of sales at Empire Standard, a cannabis extract processing and distribution plant, weighs hemp flowers on a scale on April 13, 2021 in Binghamton, New York.
(Photo by ANGELA WEISS / AFP via Getty Images)

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A Oregon researcher said cannabis compounds were equally effective against alpha and beta versions. Van Breemen said resistant versions could still emerge due to the widespread use of cannabinoids, but the combination vaccination and CBDA / CBGA treatment should create a much more demanding environment for SARS-CoV-2.

“These cannabinoids, which are orally bioavailable and have a long history of safe use in humans, have the potential to prevent and treat SARS-CoV-2 infection,” the researchers said in a published study.

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