FDA advisors recommend replacing the original covid vaccine with bivalent omicron vaccines for all doses

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A new COVID-19 booster that includes protection for Omicron at AltaMed Health Services in South Gate on Thursday, October 6, 2022.

Sarah Reingewirtz | MediaNews Group | Los Angeles Daily News via Getty Images

An independent advisory panel of the Food and Drug Administration recommended on Thursday that the original covid vaccine from Pfizer and Moderna, which is used in the US for the first two immunizations of all, be replaced with the new bivalent omicron vaccines.

If the FDA accepts the advisers’ recommendation, the US is likely to phase out corporate vaccines developed in 2020 against the original strain of Covid that first emerged in Wuhan, China.

Instead, the drug manufacturers’ bivalent omicron injections targeting the RTomicron BA.5 sub-variant as well as the original strain would be used for the entire vaccination series.

Currently, Pfizer’s and Moderna’s omicron vaccines are only approved as boosters, while the first two doses are still their old vaccines based on the original covid strain.

The potential change would only affect people who have not yet received the two-dose primary vaccination.

The recommendation to adopt a single formulation for all doses comes as the FDA tries to streamline the Covid vaccination so that the system is easier to understand by the public and healthcare professionals.

The FDA has proposed switching to a system that resembles how the agency updates and rolls out flu vaccines each year. The agency would select a formulation of the covid vaccine in June to target the variant expected to predominate in the fall and winter. This formulation would be used by all manufacturers for all doses.

Under the proposal, most people who have been exposed to the Covid spike virus twice, either through vaccination or infection, would in future only receive one Covid vaccination per year. Older adults and people with weakened immune systems may need two injections because they do not have as strong an immune response.

This is a developing story. Check for available updates.

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